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2004), those with16.2 Basic Monitoring bleeding problems, etc.). Mortality in relation to smoking: 50 years’observations on male British doctors. Consistent with its crucial role in cell growth regulation,MDM2 interacts with a large number of proteins [ 27]. Low output fistulas (< 100 mL/day) may heal rapidly with complete bowel rest,either intravenous fluids or parenteral nutrition if without food for at least 7 days, andcareful isolation of the effluent in an ostomy appliance if possible. 2013 ACC/AHA guide-line on the assessment of cardiovascular risk: a reportof the American College of Cardiology/American HeartAssociation Task Force on Practice Guidelines

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Treatment-related morbidity ismainly due to pretreatment tissue alterations and significantly increases with thecomplexity of the reconstructive procedures. Varioustechniques have been described [10, 26, 40]

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