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The presenting clinicalsymptoms include abdominal pain, anorexia and weight loss,a palpable mass, a change in bowel habits, and bloody stool.Moreover, the radiographic ?ndings of colorectal lymphomacan vary according to the histologic subtype. It was found thatduring the pairing process there was an abundance of endogenous TCR chains, but if theirnumbers were limited by using polyclonal T cell populations or by equalizing pairing usingmodified retroviral vectors, it would reduce the incidence of the syndrome (Bendle 2010).This syndrome closely resembles transfusion-associated GVHD in immunocompromisedpatients where haploidentical donor T cells attack the recipient‘s immune system and organsand is always fatal (Orlin 1997).
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Long-termtherapy may be needed in patients who tend torelapse.